Publications 2000
Role of glucose in chronic desensitization of isolated rat islets and mouse insulinoma (bTC-3) cells to glucose-dependent insulinotropic polypeptide.
Hinke, S.A.; Pauly, R.P.; Ehses, J.: Kerridge, P.: Demuth, H.-U.; McIntosh, C.H.S.; Pederson, R.A.
Journal of Endocrinology 2000, 165, 281-291.
Analogs of glucose-dependent insulinotropic polypeptide with increased dipeptidyl peptidase IV resistance.
Kühn-Wache, K.; Manhart, S.; Hoffmann, T.; Hinke, S.A.; Gelling, R.; Pederson, R.A.; McIntosh, C.H.S.; Demuth, H.-U.
Cellular peptidases in immune functions and diseases 2, 2000, 187-195.
Thioxo amino acid pyrrolidides and thiazolidides: new inhibitors of proline specific peptidases
Stöckel-Maschek, A.; MrestaniKlaus,C.; Stiebitz, B.; Demuth, H.U.; Neubert, K.
Biochim. Biophys. Acta 2000, 1479, 15-31.
Role of glucose in chronic desensitization of isolated rat islets and mouse insulinoma (Beta TC-3) cells to glucose-dependent insulinotropic polypeptide
Hinke, S.A.; Pauly, R.P.; Ehses, J.; Kerridge, P.; Demuth, H.-U.; McIntosh, C.H.S.; Pederson, R.A
J. Endocrinol. 2000 (165) 281-291
Single Dose Treatment of Diabetic Patients by the DP IV Inhibitor P32/98
Hans-Ulrich Demuth; Torsten Hoffmann; Konrad Glund; Christopher H. S. McIntosh; Raymond A. Pederson; Katja Fuecker; Sabine Fischer; Markolf Hanefeld
Diabetes 2000 (49) Suppl. 1, A102
Single dose-escalation study to investigate the safety and tolerability of the DP IV inhibitor P32/98 in healthy volunteers.
Glund, K.; Hoffmann, T.; Demuth, H.-U.; Banke-Bochita, J.; Rost, K.-L.; Fuder, H.
Exp Clin Endocrinol Diabetes 2000 (108) S159
Analogs of Glucose-dependent Insulinotropic Polypeptide with Increased Dipeptidyl Peptidase IV Resistance.
Kühn-Wache, K.; Manhart, S.; Hoffmann, T.; Hinke, S.A.; Gelling, R.; Pederson, R.A.; McIntosh, C.H.S.; Demuth, H.-U.
Advances in Experimental Medicine and Biology (Volume 477) Cellular Peptidases in Immune Functions and Diseases 2. J. Langner and S. Ansorge, eds., Kluwer/Penum Publishers, New York, 2000
Kinetic Analysis of Enzymatic and Nonenzymatic Degradation of Peptides by MALDI-TOF MS.
Rosche, F.; Schmidt, J.; Hoffmann, T.; Pauly, R.P.; McIntosh, C.H.S.; Pederson, R.A.; Demuth, H.-U.
Methods in Molecular Biology (Volume 146) Protein and Peptide Analysis. New Mass Spectrometric Applications. J.R. Chapman, ed., Humana Press Inc., Totowa, 2000
Dipeptidyl Peptidase IV (CD26) Degradation of Glucagon: Characterization of Glucagon Degradation Products and DPIV-Resistant Analogs.
Hinke, S.A.; Pospisilik, J.A.; Demuth, H.-U.; Manhart, S.; Kühn-Wache, K.; Hoffmann, T.; Nishimura, E.; Pederson, R. A.; McIntosh, C.H.S.
J. Biol. Chemistry 2000, 275 (6) 3827-3834.
Effect of Aging and Diabetes on glucose-dependent insulinotropic polypeptide and dipeptidyl peptidase IV responses to oral glucose.
Meneilly, G.S.; Demuth, H.-U.; McIntosh, C.H.S.; Pederson, R.A.
Diabetes Medicine 2000, 17, 346-350